Noninvasive imaging of thermal fields induced in soft tissues in vitro by pulsed focused ultrasound using analysis of echoes displacement
Abstract
Therapeutic and surgical applications of focused ultrasound require monitoring of local temperature rises induced inside tissues. From an economic and practical point of view ultrasonic imaging techniques seem to be the best for a temperature control. In this work an attempt to apply the method of the ultrasonic echoes displacement estimation for monitoring of local temperature rise in tissue during its heating by focused ultrasound is presented. The estimated temperature rise was compared to the data measured with thermocouple. The obtained results enable to evaluate the temperature fields induced in tissues by pulsed focused ultrasonic beams using non-invasive imaging ultrasound technique.Keywords:
HIFU, therapeutic ultrasound, ultrasonic imaging, echo strain estimationReferences
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Liu H.-L., Li M.-L., Shih T.-C., Huang S.-M., Lu I.-Y., Lin D.-Y., Lin S.-M., Ju K.-C., Instantaneous frequency-based ultrasonic temperature estimation during focused ultrasound thermal therapy, Ultrasound in Med. & Biol., 35, 10, 1647-1661, 2009.
Miller N. R., Bamber J. C., Meaney P. M., Fundamental limitations of noninvasive temperature imaging by means of ultrasounds echo strain estimation. Ultrasound in Med. & Biol., 28, 10, 1319–1333, 2002.
Souchon R., Bouchoux G., Maciejko E., Lafon C., Cathignol D., Bertrand M., Chapelon J.-Y., Monitoring the formation of thermal lesions with heatinduced echo-strain imaging: a feasibility study, Ultrasound in Med. & Biol., 31, 2, 251–259, 2005.
Bamber J. C., Hill C. R., King J. A., Acoustic properties of normal and cancerous human liver—II Dependence on tissue structure, Ultrasound Med. Biol., 7,135–144, 1981.
Guiot C., Cavalli R., Gaglioti P., Danelon D., Musacchio C., Trotta M., Todros T., Temperature monitoring using ultrasound contrast agents: in vitro investigation on thermal stability. Ultrasonics, 42, 927–930, 2004.
Haar G.ter, Therapeutic applications of ultrasound, Progress in Biophysics and Molecular Biology 93, 11-129, 2007.
Hynynen K., MRI-guided focused ultrasound treatments. Ultrasonics, 50, 221-229, 2010.
Kujawska T., Nowicki A., Lewin P. A., Determination of nonlinear medium parameter B/A using model assisted variable-length measurement approach, Ultrasonics, 51, 997-1005, 2011.
Kujawska T., Pulsed focused nonlinear acoustic fields from clinically relevant therapeutic sources in layered media: experimental data and numerical prediction results, Archives of Acoustics, 37, 3, 269, 278, 2012.
Liu H.-L., Li M.-L., Shih T.-C., Huang S.-M., Lu I.-Y., Lin D.-Y., Lin S.-M., Ju K.-C., Instantaneous frequency-based ultrasonic temperature estimation during focused ultrasound thermal therapy, Ultrasound in Med. & Biol., 35, 10, 1647-1661, 2009.
Miller N. R., Bamber J. C., Meaney P. M., Fundamental limitations of noninvasive temperature imaging by means of ultrasounds echo strain estimation. Ultrasound in Med. & Biol., 28, 10, 1319–1333, 2002.
Souchon R., Bouchoux G., Maciejko E., Lafon C., Cathignol D., Bertrand M., Chapelon J.-Y., Monitoring the formation of thermal lesions with heatinduced echo-strain imaging: a feasibility study, Ultrasound in Med. & Biol., 31, 2, 251–259, 2005.
